Clinical effects of laser photocoagulation in 160 cases of retinopathy of prematurity
نویسندگان
چکیده
Objective: This study aimed to observe the clinical effects of laser photocoagulation in treating retinopathy of prematurity (ROP), and to explore the influence of anesthesia on the disease prognosis. Methods: The study involved the retrospective analysis of 312 eyes treated with laser photocoagulation. The prognosis of ROP was observed, and its relationships with such factors as the gestational age, birth weight, age of onset, gestational age when firstly performed the laser photocoagulation correction (FPLPC), lesion site, additional lesions, photocoagulation number and anesthetic method used were analyzed. Results: The lesions present in 293 of the eyes completely resolved, while those of the remaining 19 eyes progressed (lesion regression and progression groups, respectively). The comparison of the gestational age, birth weight, age of onset, and FPLPC-gestational age between the two groups showed no statistically significant differences (t = 1.461, 0.088, 1.571, and 1.576, respectively; P > 0.05); the comparison of the anesthetic method used and the number of additional lesions too showed no significant differences between the groups (χ2 = 0.3285 and 0.203, respectively; P > 0.05). The differences in the presence of lesions in region I and the photocoagulation numbers were statistically significant between the two groups (χ2 = 18.08, P < 0.05; t = 3.522, P < 0.05, respectively). The FPLPC-gestational age and the photocoagulation numbers were correlated with the lesion progression after photocoagulation. Logistic regression analysis revealed that APROP was associated with the progress of the photocoagulation-induced postoperative pathological changes (P = 0.001). Conclusions: Laser photocoagulation is an effective treatment modality for ROP. Employing different anesthetic methods does not significantly affect the post-photocoagulation prognosis of ROP.
منابع مشابه
Transpupillary Diode Laser Retinal Photocoagulation for the Treatment of Retinopathy of Prematurity: Experience in Southern Iran
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